학력

• 1978. 3. ~ 1982. 2 서울대학교 자연과학대학 동물학과, 이학사
• 1982. 3. ~ 1984. 2. 서울대학교 자연과학대학 동물학과, 이학석사
• 1985. 9. ~ 1991. 9. Brandeis University, USA, 이학박사

주요 경력

• 1991. 9 - 1995. 2 University of Massachusetts Medical Center, USA Postdoctoral Fellow
• 1995. 3 - 2000. 2 단국대학교 분자생물학과, 전임강사/조교수
• 2000. 3 - 2001. 2 경희대학교 동서의학대학원, 조교수
• 2001. 3 - 현재 한국외국어대학교 생명공학과, 교수

Research Interests

• 알츠하이머병 및 자폐 스펙트럼 장애 치료제 개발
• 후성유전학: 염색체 구조에 의한 유전자 발현 및 복제 조절 기전 연구 

최근 논문 및 특허

• Song M., Kim H., Park S., Kwon H., Joung I., and Kwon Y.K. (2018) Aucubin Promotes Differentiation of Neural Precursor Cells into GABAergic Neurons. Exp. Neurobiol. 27, 112-119.
  
• Bae S.-E., Lyu S.K., Kim K.-J., Shin H.J., Kwon H., and Huh S. (2018) Intracellular delivery of a native functional protein using cell-penetrating peptide functionalized cubic MSN with ultra-large mesopores. Journal of Materials Chemistry B 6, 3456 – 3465.
  
• Lee A.Y., Lyu S.K., and Kwon H. (2015) BAF53 is required for mitotic progression. Animal Cells & Systems 19, 385-392.
  
• Lee K., Kim J.H., and Kwon H. (2015) Actin-related protein BAF53 is essential for chromosomal subdomain integrity. Mol. Cells 38, 789-795.
  
• Kim G.J., Yoon D.H., Yun M.Y., Kwon H., Ha H.J., and Kim H.J. (2015) An activatable fluorescent probe for targeting cellular membrane through the biothiol-mediated hydrazone-to-pyrazole transformation. Sensor. Actuat. B-Chem. 211, 245-249.
  
• Lee H., Kim D.I., Kwon H., and Kim H-.J. (2015) Bromoacetylfluorescein monoaldehyde as a fluorescence turn-on probe for cysteine over homocysteine and glutathione. Sensor. Actuat. B-Chem. 209, 652-657.
  
• Lyu S.K., and Kwon H. (2015) Preparation of cell-permeable Cre recombinase by expressed protein ligation. BMC Biotechnol. 15, 7.
  
• Lim S-.Y., Hong K-.H., Kim D.I., Kwon H., and Kim H-.J. (2014) Tunable Heptamethine-Azo Dye Conjugate as an NIR Fluorescent Probe for the Selective Detection of Mitochondrial Glutathione over Cysteine and Homocysteine. J. Am. Chem. Soc. 136, 7018-7025.
  
• Kim G-.J., Yoon D-.H., Yun M-.Y., Kwon H., Ha H-.J., and Kim H-.J. (2014) Ratiometric fluorescence probes based on a Michael acceptor type of coumarin and their application for the multichannel imaging of in vivo glutathione. RSC Adv. 4, 18731-18736.
  
• Hong K-.H., Kim D.I., Kwon H., and Kim H-.J. (2014) A fluoresceinylcarbonate-based fluorescent probe for the sensitive detection of biothiols in a HEPES buffer and its cellular e-x-p-r-e-s-s-i-o-n. RSC Adv. 4, 978-982
  
• Fe3O4-Nanoparticle-embedded multifunctional hollow mesoporous silica capsules. Hwang Y-.K., Choi J-.N., Cho J-,H., Kown H. and Huh S. 2012;Eur. J. Inorg. Chem. 21, 3379-3383
• Intracellular protein delivery by hollow mesoporous silica capsules with a large surface hole. Lim J-.S., Lee K., Choi J-.N., Hwang Y-.K., Yun M-.Y., Kim H-.J., Won Y.S., Kim S-.J., Kwon H.and Huh S.2012; Nanotechnology, 23, 085101-085111
• actin-related protein BAF53 is essential for the formation of replication foci. Kwon, S.J. and Kwon, H.2012;Animal Cells & Systems, 16, 183-189
• Suppression of HPV E6 and E7 e-x-p-r-e-s-s-i-o-n by BAF53 depletion in cervical cancer cells. Lee, K., Lee, A.Y., Kwon, Y.K. and Kwon, H. 2011.Biochem. Biophy. Res. Comm.412.328-333
• Ratiometric fluorescence imaging of cellular glutathione. Kim, G.J., Lee, K., Kwon, H.and Kim, H. J. 2011;Organic Letters 13, 2799-2801
• Coumarin-malonitrile conjugate as a fluorescence turn-on probe for biothiols and its cellular e-x-p-r-e-s-s-i-o-n. Kwon, H., Lee, K. and Kim, H.J.Chem. Comm.2011;1773-1775.
• Coumarin-malonitrile conjugate as a fluorescence turn-on probe for biothiols and its cellular e-x-p-r-e-s-s-i-o-n. KwonH,LeeK,KimHJ.ChemCommun(Camb).2011Feb14;47(6):1773-5.Epub2010Dec
• Effects of Polygala tenuifolia root extract on proliferation of neural stem cells in the hippocampal CA1 region. ParkHJ,LeeK,HeoH,LeeM,KimJW,WhangWW,KwonYK,KwonH.PhytotherRes.2008Oct;22(10):1324-9.
• Association of BAF53 with mitotic chromosomes. LeeK,ShimJH,KangMJ,KimJH,AhnJS,YooSJ,KimKwonY,KwonH.MolCells.2007Oct31;24(2):288-93.
• Shp2 is involved in neuronal differentiation of hippocampal precursor cells. KimHJ,HanAM,ShimJH,YoonHH,KwonH,KwonYK.ArchPharmRes.2007Jun;30(6):750-4.
• Expansion of chromosome territories with chromatin decompaction in BAF53-depleted interphase cells. LeeK,KangMJ,KwonSJ,KwonYK,KimKW,LimJH,KwonH.MolBiolCell.2007Oct;18(10):4013-23.Epub2007Jul25.
• Upregulation of amyloid precursor protein by platelet-derived growth factor in hippocampal precursor cells. LimJS,ChoH,HongHS,KwonH,Mook-JungI,KwonYK.Neuroreport.2007Aug6;18(12):1225-9.

특허

• 중공형 메조다공성 실리카 캡슐 및 그 제조방법. 등록번호: 10-1087260. 2011-11-21
• 중공형 메조다공성 실리카 캡슐 및 그 제조방법. 등록번호: 10-1087262. 2011-11-21
  
• 감마-L-글루타밀-L-시스테닐글라이신 검출용 조성물. 등록번호: 10-1476639. 2014-12-19
• 어큐빈을 포함하는 신경정신 질환의 예방 또는 치료용 조성물. 등록번호 10-1912544. 2018-10-22